Proven Outcomes & Evidence

Across 50+ clinical studies and evaluations — the largest body of evidence in the digital care journey category, spanning the most clinical specialties — SeamlessMD partners have reported readmission reductions up to 89%, ED visit reductions up to 72%, length of stay reductions of 1–2 days, mortality reductions up to 89%, patient phone call reductions up to 65%, and cost of care reductions of $1,000 to $9,000+ per patient episode.

Yes, across multiple institutions and specialties. Thunder Bay Regional Health Sciences Centre reported a 48% reduction across a hospital-wide, 12-program deployment (n=1,889). North Bay Regional Health Centre reported a 50% reduction across eight surgical programs (n=1,075). UAB Medicine reported a 2.7-day reduction in thoracic surgery (published, American Journal of Surgery, 2022) and a 20% reduction in gynecologic oncology (published, Gynecologic Oncology, 2023). Grand River Hospital reported a 29% reduction in hip replacement in a published matched cohort study, Halton Healthcare a 27.3% reduction in hip and knee, Horizon Health Network New Brunswick a 16.7% reduction across a province-wide cardiac program, and Baystate Health a 10% reduction in cardiac surgery.

Yes. Grand River Hospital reported an 89% reduction in readmissions and 62% reduction in ED visits in hip replacement (published, matched cohort). North Bay Regional Health Centre reported a 78% reduction in readmissions and 54% reduction in ED visits hospital-wide. Sault Area Hospital reported a 64% reduction in 30-day readmissions and 72% reduction in 30-day ED visits across nine programs. Baystate Health reported a 72% reduction in readmissions in cardiac surgery, Advocate Health a 60% reduction in readmissions and 31% reduction in ED visits in colorectal surgery, Montreal Heart Institute a 50% reduction in readmissions and 34% reduction in ED visits in TAVR (published, JACC Cardiovascular Interventions, 2022), and UAB Medicine a 50% reduction in gynecologic oncology (published, Gynecologic Oncology, 2023).

Yes, in high-acuity surgical oncology populations. Advocate Health reported an 89% reduction in 30-day mortality and 64% reduction in 90-day mortality in pancreas surgery, alongside a 20% reduction in length of stay (published, n=236). A second Advocate Health study across pancreas and liver surgery reported a 56% reduction in 30-day mortality and 24% reduction in length of stay (published, n=415).

Yes. Health systems automate PROM and PREM collection across the full episode of care, including validated instruments such as PROMIS-10, VR-12, EQ-5D, HOOS, KOOS, ESAS-R, FACT-G/FACT-C, PHQ-9 and GAD-7, with results written back into the EHR. Instruments are dynamically personalized — each patient automatically receives the measures relevant to their procedure and clinical profile. McGill University Health Centre reported 89% ERAS PRO completion, 87% agreement with a human auditor and 50% less missing data than manual abstraction (published, Surgical Endoscopy, 2017). UAB Medicine reported a 73% pre-operative PROMIS-10 and EQ-5D completion rate in thoracic surgery (published, JTCVS Open, 2025).

Yes. SeamlessMD is widely used to operationalize Enhanced Recovery After Surgery protocols, and addresses the two hardest parts of running an ERAS program at scale: getting patients to reliably complete the patient-facing elements of the protocol, and measuring compliance without manual chart audit. On the patient side, care plans deliver ERAS elements directly to the patient on the schedule the protocol specifies — pre-operative education and expectation setting, fasting and carbohydrate loading instructions, bowel preparation, early mobilization targets, diet advancement, and opioid-sparing pain management guidance — with reminders anchored to the patient’s actual surgery date and to-do lists that confirm completion. Non-completion is visible to the care team before the patient arrives, not discovered on the day of surgery.

On the measurement side, SeamlessMD automates collection of the ERAS audit data that programs otherwise fund through manual chart review. McGill University Health Centre reported 89% completion of patient-reported ERAS audit elements, 87% agreement with a human auditor, and 50% less missing data than manual abstraction (published, Surgical Endoscopy, 2017). Baystate Health’s cardiac ERAS program reported a 0.9 day LOS reduction and 72% reduction in readmissions, and Advocate Health’s colorectal ERAS program reported a 1 day LOS reduction, 60% reduction in readmissions and 31% reduction in ED visits.